SD45 905 by Frisco.org Posted on February 20, 2016 SD45 905 SD45 905 (location unknown) on November 16, 1968. This entry was posted in Slides and tagged 905, Electro-Motive Division, SD45. Bookmark the permalink.
Possibly Memphis, TN, judging from the bridge in the background?
A closer look does seem to point to Memphis. The small structure to the right in the far distance distinctly appears to be the Kentucky Street interlocking tower:
http://condrenrails.com/MRP/Memphis%20Towers%20&%20Junctions/Kentucky-Street.htm